LIVESTOCK · OWNER EDUCATION
Ketosis in Dairy Cattle
Ketosis occurs when a cow's energy demand exceeds intake around early lactation, leading to excess ketone production and reduced performance.

THE SHORT VERSION
Understanding supports better veterinary conversations.
Ketosis occurs when a cow's energy demand exceeds intake around early lactation, leading to excess ketone production and reduced performance. The same outward signs can occur with several diseases, so an examination and appropriately selected testing are important.
What is this condition?
Ketosis occurs when a cow's energy demand exceeds intake around early lactation, leading to excess ketone production and reduced performance. The same outward signs can occur with several diseases, so an examination and appropriately selected testing are important.
Which animals can be affected?
Risk factors, examination findings and management can differ between species and individual patients.
Why can it happen?
- Negative energy balance after calving.
- Reduced feed intake from another disease such as displaced abomasum, metritis or mastitis.
What might an owner notice?
- Reduced appetite—often refusal of grain—and lower milk production.
- Weight loss, firm dry manure or unusual licking and behavior in nervous ketosis.
How is the problem investigated?
- Blood, milk or urine ketone testing plus examination for an underlying disease.
- Review of transition-cow nutrition and herd patterns.
What might treatment involve?
- Veterinarian-directed glucose precursor or intravenous therapy depending on severity.
- Treatment of any disease suppressing appetite.
This is an overview, not a prescription or a recommendation for a specific individual animal.
What can owners do at home?
- Write down when the problem began and track appetite, drinking, waste, activity, breathing and medication use.
- Bring clear photos or short videos when they can be taken without stressing the animal.
- Follow the veterinary team's instructions for medication, feeding, isolation, environmental changes and rechecks.
Avoid actions that could make care less safe.
- Do not use human medication, leftover antibiotics or another animal's treatment without veterinary direction.
- Do not force food or water into an animal that cannot swallow normally, is struggling to breathe or may have an obstruction.
- Do not delay veterinary care when pain, breathing, appetite, urination, movement or responsiveness changes quickly.
What can the longer-term outlook involve?
The outlook depends on the underlying cause, severity, species and how quickly effective care begins.
Can risk be reduced?
- Provide species-appropriate nutrition, housing, sanitation and routine veterinary care.
- Learn the animal's normal behavior, appetite, body condition and waste pattern so meaningful changes are noticed early.
When should you arrange care?
- Contact a veterinarian promptly for reduced appetite—often refusal of grain—and lower milk production. or weight loss, firm dry manure or unusual licking and behavior in nervous ketosis..
- Arrange reassessment if signs return, worsen or do not improve as expected.
Seek emergency veterinary care if you notice:
SEEK EMERGENCY VETERINARY CARE- Inability to stand, severe neurologic behavior, profound weakness or concurrent severe illness.
Sources behind this guide
VeterinaryPartner — client education from the Veterinary Information NetworkPrimary veterinary or veterinary-university guidance ↗Merck Veterinary Manual: livestock healthPrimary veterinary or veterinary-university guidance ↗Content last reviewed: September 17, 2026. Review status: veterinary-informed; independent veterinarian review not yet completed.