GUINEA PIGS · OWNER EDUCATION
Urinary Stones in Guinea Pigs
Bladder or urethral stones can cause painful urination, blood in urine and sometimes complete blockage.

THE SHORT VERSION
Understanding supports better veterinary conversations.
Bladder or urethral stones can cause painful urination, blood in urine and sometimes complete blockage. The same outward signs can occur with several diseases, so an examination and appropriately selected testing are important.
What is this condition?
Bladder or urethral stones can cause painful urination, blood in urine and sometimes complete blockage. The same outward signs can occur with several diseases, so an examination and appropriately selected testing are important.
Which animals can be affected?
Risk factors, examination findings and management can differ between species and individual patients.
Why can it happen?
- Mineral-containing stones forming in the urinary tract.
- Hydration, diet, anatomy and individual mineral handling may contribute.
What might an owner notice?
- Squeaking or straining during urination and frequent small amounts.
- Blood in urine, wet rear end, reduced appetite or hunched posture.
How is the problem investigated?
- Examination, urinalysis and radiographs or ultrasound.
- Assessment of whether urine flow is blocked.
What might treatment involve?
- Pain control and removal of obstructing or problematic stones.
- Hydration and individualized diet or recurrence planning.
This is an overview, not a prescription or a recommendation for a specific individual animal.
What can owners do at home?
- Write down when the problem began and track appetite, drinking, waste, activity, breathing and medication use.
- Bring clear photos or short videos when they can be taken without stressing the animal.
- Follow the veterinary team's instructions for medication, feeding, isolation, environmental changes and rechecks.
Avoid actions that could make care less safe.
- Do not use human medication, leftover antibiotics or another animal's treatment without veterinary direction.
- Do not force food or water into an animal that cannot swallow normally, is struggling to breathe or may have an obstruction.
- Do not delay veterinary care when pain, breathing, appetite, urination, movement or responsiveness changes quickly.
What can the longer-term outlook involve?
The outlook depends on the underlying cause, severity, species and how quickly effective care begins.
Can risk be reduced?
- Provide species-appropriate nutrition, housing, sanitation and routine veterinary care.
- Learn the animal's normal behavior, appetite, body condition and waste pattern so meaningful changes are noticed early.
When should you arrange care?
- Contact a veterinarian promptly for squeaking or straining during urination and frequent small amounts. or blood in urine, wet rear end, reduced appetite or hunched posture..
- Arrange reassessment if signs return, worsen or do not improve as expected.
Seek emergency veterinary care if you notice:
SEEK EMERGENCY VETERINARY CARE- Inability to urinate, severe pain, swollen abdomen, collapse or complete appetite loss.
Sources behind this guide
VeterinaryPartner — client education from the Veterinary Information NetworkPrimary veterinary or veterinary-university guidance ↗Merck Veterinary Manual: small-mammal healthPrimary veterinary or veterinary-university guidance ↗Content last reviewed: September 17, 2026. Review status: veterinary-informed; independent veterinarian review not yet completed.